Vyvanse (vyvanse chewable) is the brand name for Lisdexamfetamine useful in treating Attention Deficit Hyperactivity Disorder in children above five years of age and binge eating disorder in adults. Vyvanse comes as an oral medication with therapeutic effects starting within 2 hours and lasting for about 12 hours.
Vyvanse is a central nervous system stimulant. The Lisdexamfetamine in the medication gets converted to dextroamphetamine in the body. It got approval for medical use in the year 2007 in America. Vyvanse was the 99th among the top 100 most prescribed medications in the USA with above 7 million prescriptions in 2016.
The medication is a schedule-II controlled substance under the Controlled Substance Act due to associated risks of abuse, dependence, misuse, and diversion.
Vyvanse comes in the formulations of capsules (containing 10, 20, 30, 40, 50, 60, and 70 milligrams of Lisdexamfetamine dimesylate) and chewable tablets (10, 20, 30, 40, 50, and 60 milligrams of Lisdexamfetamine dimesylate).s489
Vyvanse capsules contain inactive ingredients such as croscarmellose sodium, microcrystalline cellulose, magnesium stearate, and FDA approved color additives. The chewable tablets contain inactive ingredients such as croscarmellose sodium, colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, mannitol, sucralose, and artificial strawberry flavor. 140 mg vyvanse
Lisdexamfetamine is primarily helpful for the treatment of ADHD (attention deficit hyperactivity disorder) and binge eating disorder. It has similar pharmaceutical effects like amphetamines. Vyvanse is not recommendable for individuals above 65 years of age. In individuals with ADHD, Vyvanse improves brain development and nerve growth.
Reviews of MRI studies suggest that Vyvanse long-term treatment can decrease brain structure abnormalities in people with ADHD and improves the functioning of several parts of the brain such as the basal ganglia’s right caudate nucleus. It is a medication that is useful for the long-term treatment of attention deficit hyperactivity disorder.
Although Vyvanse helps treat moderate to severe Binge Eating Disorder (BED), It is not advisable to use the medicine for weight loss. The use of sympathomimetic drugs such as Vyvanse for weight loss results in severe adverse cardiovascular effects. There is no establishment of the safety and effectiveness of medicine for obesity treatment or weight loss.
Physical side effects of Vyvanse vary from person to person at normal therapeutic doses. Cardiovascular effects including hypotension or hypertension, tachycardia, and Raynaud’s phenomenon. Sexual effects in males include prolonged or frequent erections or erectile dysfunctions. Gastrointestinal side effects may include constipation, abdominal pain, nausea, and diarrhea.
Other potential physical adverse effects include loss of appetite, dry mouth, blurred vision, excessive teeth grinding, bleeding nose, profuse sweating, nasal congestion, tics, and weight loss. At usual pharmaceutical doses, Vyvanse rarely has any life-threatening effects.
Lisdexamfetamine stimulates the medullary respiratory center thus producing deeper and faster breaths. The effects are usually unnoticeable in normal adults, but they can be dangerous for people with compromised respiratory functions.s489 30